Science is one of six Champion Classes. It has a Class Bonus against Mystic, but is weak to Skill and Combined.


Many characters in the Science class were genetically altered, often in freak accidents. However, some characters are instead unaltered but rely on science to fight.

Class Bonus

  • The high base attributes of Science Champions cannot be nullified or purged by Mystic Champions.
  • Frequent Bleed damage from Skill Champions is effective against the high base attributes of Science Champions.
  • Science is also weak to the Combined Class, exclusive to Maestro.

List of Science Champions

See the associated category: Science.


  • Science currently has the lowest number of Champions with 16.


Science List of Science Champions Science

Playable: AbominationAnt-ManCaptain America (WWII) ● ElectroHulkJoe FixitLuke CageM.O.D.O.K.QuakeRed HulkRhinoSentryShe-HulkSpider-Gwen ● Spider-Man (ClassicMiles Morales) ● VoidYellowjacket
Not playable: AdaptoidDarren CrossDeadpooloidElectro LukeJessica JonesRed SkullSpider-WitchSymbioidUltron Drone
Upcoming: Wasp

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